Hormone sex change

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In transgender men, or trans masculine people FTM , the most common medication used for transition is testosterone. Administration of testosterone via transdermal, intramuscular, subcutaneous, or oral routes lowers serum estradiol levels, raises serum testosterone levels, and results in the development of typical male secondary sex characteristics. Irreversible changes include: deepening of the voice, increase in facial and body hair growth, clitoral enlargement clitoromegaly , and thickened facial bone structure. Some trans men also describe changes in emotions e. Adverse effects can include elevations in blood pressure, polycythemia, worsening of lipid profile, elevations in glucose, elevations in transaminases, acne, and effects on fertility although testosterone is not an effective contraceptive as it does not interrupt ovulation, so pregnancy can still occur.
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Transgender hormone therapy (male-to-female)

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Feminizing hormone therapy - Mayo Clinic

Feminizing hormone therapy is used to induce physical changes in your body caused by female hormones during puberty secondary sex characteristics to promote the matching of your gender identity and your body gender congruence. If feminizing hormone therapy is started before the changes of male puberty begin, male secondary sex characteristics, such as increased body hair and changes in voice pitch, can be avoided. Feminizing hormone therapy is also referred to as cross-sex hormone therapy. During feminizing hormone therapy, you'll be given medication to block the action of the hormone testosterone. You'll also be given the hormone estrogen to decrease testosterone production and induce feminine secondary sex characteristics.
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What are commonly used medications for transition?

Many transgender men and women seek hormone therapy as part of the transition process. Exogenous testosterone is used in transgender men to induce virilization and suppress feminizing characteristics. In transgender women, exogenous estrogen is used to help feminize patients, and anti-androgens are used as adjuncts to help suppress masculinizing features.
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Transgender hormone therapy of the male-to-female MTF type, also known as transfeminine hormone therapy , is hormone therapy and sex reassignment therapy to change the secondary sexual characteristics of transgender people from masculine or androgynous to feminine. Some intersex people also take this form of therapy, according to their personal needs and preferences. The purpose of the therapy is to cause the development of the secondary sex characteristics of the desired sex , such as breasts and a feminine pattern of hair , fat , and muscle distribution.

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